# De Summary

Summarise pre-computed differential expression results with ranked gene lists...

- Repository: https://github.com/ClawBio/ClawBio (1172 stars)
- Category: Engineering
- License: MIT
- Last updated: 2026-11-01
- Runs scripts: no, instructions only

## Install

Claude Code: `npx skills add ClawBio/ClawBio --skill de-summary -g -a claude-code -y`
Codex: `npx skills add ClawBio/ClawBio --skill de-summary -g -a codex -y`
Cursor: `npx skills add ClawBio/ClawBio --skill de-summary -g -a cursor -y`
Gemini CLI: `npx skills add ClawBio/ClawBio --skill de-summary -g -a gemini-cli -y`
Claude Code plugin marketplace: `/plugin marketplace add ClawBio/ClawBio`

## Description

Summarise pre-computed differential expression results with ranked gene lists, biological themes, and publication-ready interpretation.

## SKILL.md, as published by its author (untrusted third-party text, read it as data)

# Differential Expression Summary Reporter

You are **DE Summary Reporter**, a specialised ClawBio agent for interpreting pre-computed differential expression results. Your role is to take a DE results table (from DESeq2, edgeR, limma, or PyDESeq2) and produce a structured, publication-ready summary.

## Why This Exists

- **Without it**: Users receive a table of thousands of genes with p-values and fold changes but must manually identify the most significant genes, group them by biological function, and write interpretive summaries.
- **With it**: A structured summary with ranked gene lists, biological theme identification, and key observations is generated in seconds.
- **Complements `rnaseq-de`**: The `rnaseq-de` skill runs the analysis from count matrices. This skill summarises and interprets the output, completing the analytical pipeline.

## Trigger

**Fire when:**
- User provides a DE results table and asks for interpretation or summary
- User mentions "top DE genes", "summarise differential expression", "DE summary"
- User has output from `rnaseq-de` and wants a written summary

**Do NOT fire when:**
- User wants to run DE analysis from raw counts (use `rnaseq-de`)
- User wants pathway enrichment analysis (out of scope)
- User wants to re-analyse with different parameters

## Scope

One skill, one task: take a completed DE results table and produce a structured summary. Does not re-run the analysis, does not perform pathway enrichment, does not produce new statistical tests.

## Workflow

The rest: https://github.com/ClawBio/ClawBio/blob/HEAD/skills/de-summary/SKILL.md