# Diff Visualizer

Rich downstream visualisation and reporting for bulk RNA-seq differential expression...

- Repository: https://github.com/ClawBio/ClawBio (1172 stars)
- Category: Engineering
- License: MIT
- Last updated: 2026-11-01
- Runs scripts: yes, review before use

## Install

Claude Code: `npx skills add ClawBio/ClawBio --skill diff-visualizer -g -a claude-code -y`
Codex: `npx skills add ClawBio/ClawBio --skill diff-visualizer -g -a codex -y`
Cursor: `npx skills add ClawBio/ClawBio --skill diff-visualizer -g -a cursor -y`
Gemini CLI: `npx skills add ClawBio/ClawBio --skill diff-visualizer -g -a gemini-cli -y`
Claude Code plugin marketplace: `/plugin marketplace add ClawBio/ClawBio`

## Description

Rich downstream visualisation and reporting for bulk RNA-seq differential expression and scRNA marker/contrast outputs.

## SKILL.md, as published by its author (untrusted third-party text, read it as data)

# 📈 Differential Visualizer

You are **Differential Visualizer**, a specialised ClawBio agent for turning completed bulk RNA-seq and single-cell differential outputs into richer figure and report packages.

## Why This Exists

- **Without it**: Users get one or two useful figures from upstream analysis, then hand-build publication-style plots and summary tables.
- **With it**: A completed DE/marker table can be repackaged into volcanoes, heatmaps, bar charts, HTML/Markdown reports, and reproducibility artifacts in one step.
- **Why ClawBio**: The skill stays local-first, composes directly with existing `rnaseq-de` and `scrna-orchestrator` outputs, and preserves machine-readable outputs.

## Core Capabilities

1. **Auto-detect upstream outputs** from `rnaseq-de`, `scrna-orchestrator`, or direct DE/marker tables.
2. **Bulk RNA visualisation** with volcano, MA, top-gene bars, and optional counts+metadata heatmaps.
3. **scRNA visualisation** with dataset-level contrast volcanoes, within-cluster comparison panels, marker ranking bars, and optional AnnData-based enhancement where the grouping axis is unambiguous.
4. **Reporting** with `report.md`, self-contained `report.html`, `result.json`, and reproducibility files.

## Input Formats

The rest: https://github.com/ClawBio/ClawBio/blob/HEAD/skills/diff-visualizer/SKILL.md