Openfold3 Nim
Use this skill for OpenFold3, NVIDIA's BioNeMo NIM microservice for biomolecular...
Install
npx skills add NVIDIA/skills --skill openfold3-nim -g -a claude-code -y- Repository
- NVIDIA/skills3.8k
- Category
- DevOps
- Updated
- 5d ago
- License
- Apache-2.0 AND CC-BY-4.0
- Context cost
- Mediumabout 1,757 tokens
- Runs scripts
- No, instructions only
What it does
Use this skill for OpenFold3, NVIDIA's BioNeMo NIM microservice for biomolecular structure prediction. Invoke whenever the user mentions OpenFold3 or needs protein, protein-ligand, protein-DNA/RNA, or multi-chain complex prediction with the hosted NVIDIA API or local Docker NIM. Covers endpoint choice, auth, request payloads, output artifacts, confidence scores, and local container setup.
OpenFold3 NIM
Predict biomolecular structures with OpenFold3. It supports proteins, DNA, RNA, small-molecule ligands, and multi-entity assemblies. Use this guide for basic hosted and local NIM use; load supplemental files only when the task needs deeper context:
references/api.md: exact endpoints, schemas, Docker flags, response fields.references/science.md: purpose, strengths, limitations, and model handoffs.references/parameters.md: molecule fields, MSAs, templates, samples, tuning.references/validation.md: artifact checks and scientific sanity checks.references/examples.md: compact hosted and local request patterns.
Choose Mode
Ask only when context is unclear:
Hosted NVIDIA API or local Docker NIM?
- Hosted URL:
https://health.api.nvidia.com/v1/biology/openfold/openfold3/predict - Local URL:
http://localhost:8000/biology/openfold/openfold3/predict - Local readiness:
http://localhost:8000/v1/health/ready
Mode difference: the local prediction path has no /v1/ prefix. Hosted requests use Authorization: Bearer $NGC_API_KEY. Supported local Docker
startup uses NGC_API_KEY (or NVIDIA_API_KEY via the preflight) for
registry login, entitlement checks, and first-run model downloads; pass it
into the container with -e NGC_API_KEY. Local inference requests use no
auth header after readiness, so bind the host port to loopback with
-p 127.0.0.1:8000:8000. Warm-cache key-free startup varies by image version
and should not be assumed.
Auth And Environment
Use credentials already supplied in the environment or injected by a secret manager. Do not load credential files, print keys, or enable shell tracing. Confirm keys exist with shell tests.
Hosted needs NGC_API_KEY in the request header. Local startup needs
NGC_API_KEY, or NVIDIA_API_KEY as a fallback, plus LOCAL_NIM_CACHE.
