Skills

Rfd4 Proteina Nim

Run RFD4-Proteina NIM for joint protein structure and sequence design, conditioned...

Install

npx skills add NVIDIA/skills --skill rfd4-proteina-nim -g -a claude-code -y
Repository
NVIDIA/skills3.8k
Category
Design
Updated
5d ago
License
Apache-2.0
Context cost
Mediumabout 2,482 tokens
Runs scripts
Yes, review before use

What it does

Run RFD4-Proteina NIM for joint protein structure and sequence design, conditioned generation, and reward-guided search using the NVIDIA hosted API or a self-hosted NIM. Not for the older RFdiffusion contigs API.

RFD4-Proteina NIM

Generate protein structures and sequences through the released RFD4-Proteina NIM. This skill covers conditioned protein and small-molecule binders, motif and enzyme scaffolding, antibody/CDR design, partial diffusion, inverse folding, and reward-guided beam search. Use science for interpretation.

Prerequisites

Use Python 3.10 or newer; the client uses only the standard library. Hosted inference requires a key obtained from the product page, set as NVIDIA_API_KEY (NGC_API_KEY is accepted as a fallback). Supply the key through the user's secret mechanism, not a prompt or command-line argument. Offline preparation and saved-response extraction need no credentials.

For an existing local NIM, use its base URL. Starting a new container also requires Docker, NVIDIA Container Toolkit, a supported GPU/driver, and NGC access; read deployment only when deployment is needed.

Instructions

Read the whole SKILL.md on GitHub

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