Skills

Cerna Analysis

Use when building a ceRNA regulatory network from a key gene list by combining bundled...

Install

npx skills add aipoch/medical-research-skills --skill cerna-analysis -g -a claude-code -y
Category
Documents
Updated
2mo ago
License
MIT
Context cost
Mediumabout 2,300 tokens
Runs scripts
No, instructions only

What it does

Use when building a ceRNA regulatory network from a key gene list by combining bundled miRNA-mRNA and miRNA-lncRNA database files, with flat-file CSV exports and PDF visualization in a single output directory. NOT for: differential expression, single-cell analysis, enrichment analysis, or workflows without a key gene list.

ceRNA Analysis

When to Use

Use this skill when you need to construct a ceRNA regulatory network from a known key-gene list using the bundled miRNA-mRNA and miRNA-lncRNA reference tables.

Use it for:

  • Building a ceRNA network from one gene list and exporting flat CSV plus PDF outputs
  • Comparing supported miRNA source modes such as combined, starbase, or pairwise overlaps
  • Re-running the same local workflow with different lncRNA strictness, layout, or plotting parameters

Do not use it for:

  • Differential expression, single-cell, enrichment, or survival analysis
  • Workflows that do not start from a key gene list
  • Cases where you want a miRNA-mRNA-only graph without a retained lncRNA ceRNA layer

Input Validation

This skill accepts:

  • A key gene list as a plain-text file (one gene symbol per line) or as a comma-separated string on the CLI
  • Optional parameter overrides for dataset mode, lncRNA strictness, layout, colors, and timeout

If the user's request does not involve building a ceRNA regulatory network from a key gene list, for example, asking to run differential expression, enrichment analysis, single-cell workflows, or survival analysis, do not proceed with the workflow. Instead respond:

"ceRNA Analysis is designed to construct a ceRNA regulatory network from a key gene list using bundled miRNA-mRNA and miRNA-lncRNA reference databases. Your request appears to be outside this scope. Please provide a key gene list and specify a supported miRNA dataset mode, or use a more appropriate skill for differential expression, enrichment analysis, or single-cell workflows."

When to Read External Files

Read the whole SKILL.md on GitHub

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