Skills

Parsing Trial Eligibility

Parses free-text clinical-trial eligibility criteria into structured inclusion and...

Install

npx skills add maziyarpanahi/openmed --skill parsing-trial-eligibility -g -a claude-code -y
Repository
maziyarpanahi/openmed5.8k
Category
Engineering
Updated
4d ago
License
Apache-2.0
Context cost
Mediumabout 1,820 tokens
Runs scripts
No, instructions only

What it does

Parses free-text clinical-trial eligibility criteria into structured inclusion and exclusion logic, then matches them against patient facts that OpenMed extracted. Use when the user wants to turn a ClinicalTrials.gov eligibility block into machine-readable rules, screen a synthetic patient for trial fit, or explain why a patient does or does not meet criteria. Trigger keywords: eligibility criteria, inclusion, exclusion, trial matching, patient screening, criteria parsing, eligibilityModule, age/sex gates. Pairs after OpenMed and after searching-clinicaltrials: consume the eligibilityModule text from a study, structure it, and match against conditions, medications, labs, and demographics from openmed.analyze_text. Decision-support only, never autonomous enrollment.

Parsing trial eligibility & matching patients

A ClinicalTrials.gov study exposes its eligibility as a single free-text block (protocolSection.eligibilityModule.eligibilityCriteria) plus a few typed fields (sex, minimumAge, maximumAge, healthyVolunteers). This skill turns that prose into structured inclusion / exclusion criteria and matches each rule against patient facts that OpenMed extracted, producing an explainable eligible | ineligible | unknown verdict per criterion.

This is decision support, not enrollment. The output is a candidate list and a rationale for a clinician to review, never an automated eligibility decision.

When to use

  • You pulled a study with searching-clinicaltrials and need its eligibility as machine-readable rules.
  • You have a (synthetic) patient profile and want to screen it against one or many trials, with a per-criterion reason.
  • You want to highlight which patient facts are missing to decide a criterion.

Quick start

The typed gates are deterministic, apply them first. The free-text criteria need parsing into bullet-level inclusion/exclusion items.

# Study from ClinicalTrials.gov v2 (see searching-clinicaltrials)
elig = study["protocolSection"]["eligibilityModule"]

raw = elig["eligibilityCriteria"]            # free text, often markdown bullets
sex = elig.get("sex", "ALL")                 # ALL | FEMALE | MALE
min_age = elig.get("minimumAge")             # e.g. "18 Years"
max_age = elig.get("maximumAge")             # e.g. "75 Years"
healthy_ok = elig.get("healthyVolunteers")   # bool
Read the whole SKILL.md on GitHub

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